|
Peer-Reviewed Publications
|
|
2009
|
47. |
"Controlling Ribozyme Activity by Metal Ions"
Joachim Schnabl, Roland K. O. Sigel*
Curr. Op. Chem. Biol., 2009, in press.
|
46. |
"Solution structure of a DNA double helix with consecutive metal-mediated base pairs"
Silke Johannsen, Nicole Megger, Dominik Böhme, Roland K. O. Sigel,* Jens Müller*
Nature Chem., 2009, in press.
|
45. |
"Ca2+ Induces the Formation of Two Distinct Subpopulations of Single Group II Intron Molecules"
Miriam Steiner, David Rueda*, Roland K. O. Sigel*
Angew. Chem., 2009, available online, doi: 10.1002/ange.200903809.
|
44. |
"Exploring Metal Ion Coordination to Nucleic Acids by NMR"
Silke Johannsen, Maximiliane M. T. Korth, Joachim Schnabl, Roland K. O. Sigel*
Chimia, 2009, 63, 146-152.
Invited contribution to the special issue "Young Academics in Switzerland"
|
43. |
"Influence of Decreased Solvent Permittivity on the Structure and Magnesium(II)-Binding Properties of the Catalytic Domain 5 of a Group II Intron Ribozyme"
Maya Furler, Bernd Knobloch, Roland K. O. Sigel*
Inorg. Chim. Acta, 2009, 362, 771-776.
Invited article for the special issue in honor of Bernhard Lippert, University of Dortmund
|
|
2008
|
42. |
"Divalent Metal Ions Promote the Formation of the 5'-Splice Site Recognition Complex in a Self-Splicing Group II Intron"
Daniela Kruschel, Roland K. O. Sigel*
J. Inorg. Biochem., 2008, 102, 2147-2154.
|
41. |
"Effect of the Ribose versus 2'-Deoxyribose Residue on the Metal Ion-Binding Properties of Purine Nucleotides"
Ariel Mucha, Bernd Knobloch, Malgorzata Jezowska-Bojczuk, Henryk Kozlowski, Roland K. O. Sigel*
Dalton Trans., 2008, 5368 - 5377.
|
40. |
"Single Molecule Studies of Group II Intron Ribozymes"
Miriam Steiner, Krishanti S. Karunatilaka, Roland K. O. Sigel*, David Rueda*
Proc. Natl. Acad. Sci. USA, 2008, 105, 13853-13858.
|
39. |
"Divalent Metal Ions Tune the Self-Splicing Reaction of the Yeast Mitochondrial Group II Intron Sc.ai5γ"
Michele C. Erat, Roland K. O. Sigel*
J. Biol. Inorg. Chem., 2008, 13, 1025-1036.
|
38. |
"Comparison of the Acid-Base Properties of Ribose and 2-Deoxyribose Nucleotides"
Ariel Mucha, Bernd Knobloch, Malgorzata Jezowska-Bojczuk, Henryk Kozlowski, Roland K. O. Sigel*
Chem. Eur. J., 2008, 14, 6663-6671.
|
37. |
"The Corrin Moiety of Coenzyme B12 is the Determinant for Switching the btuB Riboswitch of E. coli"
Sofia Gallo, Michael Oberhuber, Roland K. O. Sigel*, Bernhard Kräutler*
ChemBioChem, 2008, 9, 1408-1414.
|
36. |
"Using In Vitro Transcription to Construct Scaffolds for One-Dimensional Arrays of Mercuric Ions"
Silke Johannsen, Susann Paulus, Nicole Düpre, Jens Müller*, Roland K. O. Sigel*
J. Inorg. Biochem., 2008, 102, 1141-1151.
|
35. |
"Discrimination in Metal Ion Binding to RNA Dinucleotides with a Terminal Oxygen or Sulfur in the Phosphate Diester Link (pUpU3- and pUp(S)U3-)"
Bernd Knobloch, Barbara Nawrot, Andrzej Okruszek, Roland K. O. Sigel*
Chem. Eur. J., 2008, 14, 3100-3109.
|
34. |
"Metal Ion-Nucleic Acid Interactions"
Roland K. O. Sigel*
in Nucleic Acids from A to Z - A Concise Encyclopedia, Sabine Müller (Editor), Wiley-VCH, Weinheim, 2008, 350 p.
ISBN-10: 3-527-31211-0; ISBN-13: 978-3-527-31211-5.
|
|
2007
|
33. |
"Determination of the Intrinsic Affinities of Multiple Site-Specific Mg2+ Ions Coordinated to Domain 6 of a Group II Intron Ribozyme"
Michele C. Erat, Roland K. O. Sigel*
Inorg. Chem., 2007, 46, 11224-11234.
|
32. |
"Binding Interaction of [Re(H2O)3(CO)3]+ with the DNA Fragment d(CpGpG)"
Fabio Zobi*, Olivier Blacque, Roland K. O. Sigel, Roger Alberto
Inorg. Chem., 2007, 46, 10458-10460.
|
31. |
"From Nucleotides to Ribozymes - A Comparison of Their Metal Ion-Binding Properties"
Eva Freisinger, Roland K. O. Sigel*
Coord. Chem. Rev., 2007, 251, 1834-1851.
|
30. |
"Metal Ion-Coordinating Properties of the Dinucleotide 2'-Deoxyguanylyl(5'->3')-2'-deoxy-5'-guanylate, d(pGpG)3-"
Bernd Knobloch, Helmut Sigel, Andrzej Okruszek, Roland K. O. Sigel*
Chem. Eur. J., 2007, 13, 1804-1814.
|
29. |
"Solution Structure of Domain 6 from a Self-Splicing Group II Intron Ribozyme: A Mg2+ Binding Site is Located Close to the Stacked Branch Adenosine"
Michele C. Erat, Oliver Zerbe, Thomas Fox, Roland K. O. Sigel*
ChemBioChem, 2007, 8/3, 306-314.
Selected for Cover illustration of this issue.
|
28. |
"Alternative Roles for Metal Ions in Enzyme Catalysis and the Implications for Ribozyme Chemistry"
Roland K. O. Sigel*, Anna Marie Pyle*
Chem. Rev., 2007, 107, 97-113.
|
27. |
"Complex Formation of Nickel(II) with Sugar Residues, Nucleobases, Phosphates, Nucleotides, and Nucleic Acids"
Roland K. O. Sigel*, Helmut Sigel*
Met. Ions. Life Sci., 2007, 2, 109-180.
|
26. |
"Towards the Synthesis of Light Stable Coenzyme B12 Analogs"
Sofia Gallo, Eva Freisinger, Roland K. O. Sigel*
Inorg. Chim. Acta, 2007, 360, 360-368.
Invited article for the special issue "Inorganic Chemistry - The Next Generation
|
|
2006
|
25. |
"Acid-Base Properties of the Nucleic-Acid Model 2'-Deoxyguanylyl(5'®3')-2'-deoxy-5'-guanylate, d(pGpG)3-, and of Related Guanine Derivatives"
Bernd Knobloch, Helmut Sigel, Andrzej Okruszek, Roland K. O. Sigel*
Org. Biomol. Chem., 2006, 4, 1085-1090.
|
24. |
"Pyrazine as a Building Block for Molecular Architectures with PtII"
Michael Willermann, Clodagh Mulcahy, Roland K. O. Sigel, Marta Morell Cerdà, Eva Freisinger, Pablo J. Sanz Miguel, Michael Roitzsch, Bernhard Lippert*
Inorg. Chem., 2006, 45, 2093-2099.
|
|
2005
|
23. |
"Structure Determination of Catalytic RNAs and Investigations on Their Metal Ion Binding Properties"
Michele Erat, Roland K. O. Sigel*
CHIMIA, 2005, 59, 817-821.
|
22. |
"In Vitro Transcription and Purification of RNAs of Different Size"
Sofia Gallo, Maya Furler, Roland K. O. Sigel*
CHIMIA, 2005, 59, 812-816.
|
21. |
"Acid-Base and Metal Ion-Binding Properties of the RNA-Dinucleotide Uridylyl-(5'->3')-[5']uridylate (pUpU3-)"
Bernd Knobloch, Danuta Suliga, Andrzej Okruszek, Roland K. O. Sigel*
Chem. Eur. J., 2005, 11, 4163-4170.
|
20. |
"Group II Intron Ribozymes and Metal Ions - a Delicate Relationship"
Roland K. O. Sigel*
Eur. J. Inorg. Chem., 2005, 12, 2281-2292.
|
|
2004
|
19. |
"Two Metal Ions Coordinated to a Purine Residue Tolerate Each Other Well!"
Bernd Knobloch, Roland K. O. Sigel*, Bernhard Lippert, Helmut Sigel
Angew. Chem. Int. Ed., 2004, 43, 3793-3795
Angew. Chem., 2004, 116, 3881-3883.
|
18. |
"The solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif"
Roland K. O. Sigel, Dipali G. Sashital, Dana L. Abramovitz, Samuel E. Butcher*, Arthur G. Palmer III, Anna Marie Pyle*
Nature Struct. Mol. Biol., 2004, 11/2, 187-192.
|
|
2003
|
17. |
"Lanthanide Ions as Structural Probes for Metal-Ion Binding Sites in Ribozymes"
Roland K. O. Sigel*, Anna Marie Pyle*
Met. Ions Biol. Syst., 2003, 40, 477-512.
|
|
2002
|
16. |
"Hydrogen Bonding Patterns of 7,9-Dimethylguanine and its Transplatinum(II) Complexes"
Roland K. O. Sigel, Eva Freisinger, Michele Abbate, Bernhard Lippert*
Inorg. Chim. Acta, 2002, 339, 355-365.
|
15. |
"N1 and N3 Linkage Isomers of Neutral and Deprotonated Cytosine with trans[(CH3NH2)2PtII]"
Wolfgang Brüning, Eva Freisinger, Michal Sabat, Roland K. O. Sigel, Bernhard Lippert*
Chem. Eur. J., 2002, 8, 4681-4692.
|
|
2001
|
14. |
"PtII Binding to N1 of Cytosine: Strengthening the Watson-Crick Pair with Guanine and yet Confining Its pH Existence Range"
Wolfgang Brüning, Roland K. O. Sigel, Eva Freisinger, Bernhard Lippert*
Angew. Chem. Int. Ed., 2001, 40, 3397-3399
Angew. Chem., 2001, 113, 3497-3500.
|
13. |
"Metal-Modified Nucleobase Sextet: Joining Four Linear Metal Fragments (trans-a2PtII and Six Model Nucleobases to an Exceedingly Stable Entity"
Roland K. O. Sigel, Susan M. Thompson, Eva Freisinger, Frank Glahé, Bernhard Lippert*
Chem.-Eur. J., 2001, 7, 1968-1980.
|
|
2000
|
12. |
"Metal Ion Binding Sites in a Group II Intron Core"
Roland K. O. Sigel, Anand Vaidya, Anna Marie Pyle*
Nature Struct. Biol., 2000, 7/12, 1111-1116.
|
11. |
"Effects of N7-Methylation, N7-Platination, and C8-Hydroxylation of Guanine on H-Bond Formation with Cytosine: Platinum Coordination Strengthens the Watson-Crick Pair"
Roland K. O. Sigel, Eva Freisinger, Bernhard Lippert*
J. Biol. Inorg. Chem., 2000, 5, 287-299.
|
10. |
"Heavy Metal Mutagenicity: Insights from Bioinorganic Model Chemistry"
Jens Müller, Roland K. O. Sigel, Bernhard Lippert*
J. Inorg. Biochem., 2000, 79, 265-269.
|
9. |
"Hydrogen Bonding Between Adenine and 2,4-Difluorotoluene is Definitely
not Present, as Shown by Concentration-Dependent NMR Studies"
Kathrin S. Schmidt, Roland K. O. Sigel, Dmitri V. Fillipov, Gijs A. van der Marel, Bernhard Lippert, Jan Reedijk*
New J. Chem., 2000, 195-197.
|
|
1999
|
8. |
"Platinum(II) Coordination to Guanine-N7: Enhancement of the Watson-Crick-Base-Pair with Cytosine"
Roland K. O. Sigel, Bernhard Lippert*
Chem. Commun., 1999, 2167-2168.
|
7. |
"Metal-Modified Base Pairs Involving Different Donor Sites of Purine Nucleobases: trans-[a2Pt(7,9-DimeG-N1)(9-EtGH-N7)]2+ and trans-[a2Pt(7,9-DimeG-N1)(9-EtG-N7)]+ (a = NH3 or CH3NH2; 9-EtGH = 9-ethylguanine; 7,9-DimeG = 7,9-dimethylguanine). Possible Relevance to Metalated DNA Triplex Structures"
Roland K. O. Sigel, Michal Sabat, Eva Freisinger, Amanda Mower, Bernhard Lippert*
Inorg. Chem., 1999, 38, 1481-1490.
|
6. |
"Combining Four Different Model Nucleobases (Uracil, Adenine, Guanine, Cytosine) via Metal Binding and H Bond Formation in a Single Compound"
Roland K. O. Sigel, Susan M. Thompson, Eva Freisinger, Bernhard Lippert*
Chem. Commun., 1999, 19-20.
|
|
1998
|
5. |
"Metalated Nucleobase Quartets: Dimerization of a Metal-Modified Guanine, Cytosine Pair of trans-(NH3)2PtII and a Case of CH---N Hydrogen Bonding"
Roland K. O. Sigel, Eva Freisinger, Bernhard Lippert*
J. Am. Chem. Soc., 1998, 120, 12000-12007.
|
4. |
"Creating Regular Arrangements of Nucleobases through Metal Ion Coordination and H Bond Formation"
Bernhard Lippert*, Pilar Amo-Ochoa, Wolfgang Brüning, Eva Freisinger,
Marc-Sven Lüth, Susanne Meier, Cordula Meiser, Susanne Metzger, Holger
Rauter, André Schreiber, Roland K. O. Sigel, Holger Witkowski
Pure & Appl. Chem., 1998, 70, 977-983.
|
3. |
"If Watson-Crick and Hoogsteen Sites of Guanine are Blocked, H Bonding with Cytosine is via N2 and N3"
Roland K. O. Sigel, Eva Freisinger, Bernhard Lippert*
Chem. Commun., 1998, 219-220.
|
|
1997
|
2. |
"Stabilities and Structures of Metal Ion Complexes of Adenosine 5'-O-Thiomonophosphate (AMPS2-) in Comparison with Those of Its Parent Nucleotide (AMP2-) in Aqueous Solution"
Roland K. O. Sigel, Bin Song, H. Sigel*
J. Am. Chem. Soc., 1997, 119, 744-755.
|
1. |
"Acid-Base Properties of Adenosine 5'-O-Thiomonophosphate in Aqueous Solution"
Bin Song, Roland K. O. Sigel, H. Sigel*
Chem. Eur. J., 1997, 3, 29-33.
|
|
Conference Reports and Further Publications
|
5. |
"Nucleic Acid-Metal Ion Interactions"
Roland K. O. Sigel*
Chemistry World, 2009, issue 4, 60-61.
-- Book recension: Nucleic Acid-Metal Ion Interactions, Nicholas V. Hud, RSC Publishing, 2009, 447 pp. ISBN 978-0-85404-195-4
|
4. |
"Vanadium: The Versatile Metal"
Roland K. O. Sigel*
Angew. Chem. Int. Ed., 2009, 48, 1888-1889.
Angew. Chem., 2009, 121, 1920-1921.
-- Book recension: The Versatile Metal, Kenneth Kustin, João Costa Pessoa, Debbie C. Crans (Eds.), Am. Chem. Soc. Washington DC, 2007, 448 pp. ISBN 978-0-84127-446-4
|
3. |
"Graduate School of Chemical and Molecular Sciences Zurich (CMSZH)"
Roland K. O. Sigel*, Ferdinand Wild*
CHIMIA, 2008, 62, 130-131.
ISSN: 0570-0833
|
2. |
"In the Footsteps of Alfred Werner: The Institute of Inorganic Chemistry at the University of Zurich"
Roger Alberto, Greta R. Patzke, Roland K. O. Sigel, Heinz G. Berke*
CHIMIA, 2008, 62, 111-113.
ISSN: 0570-0833
|
1. |
"Intimate Relationships Between Metal Ions and Nucleic Acids"
Roland K. O. Sigel*
Angew. Chem. Int. Ed., 2007, 46, 654-656.
Angew. Chem., 2007, 119, 664-666.
Conference Review for <ESF-COST High-Level Research Conference in Inorganic Chemistry on Metal-Nucleic Acid Interactions, November 12-17, 2006, Athens, Greece."
|
|
Books
|
1. |
"Effect of Platinum(II) Coordination on the Acid-Base and Hydrogen-Bonding Properties of Nucleobases: Association Patterns in Solution and the Solid State"
Roland K. O. Sigel
Logos Verlag, Berlin, Germany, 1999, 235 pp.
ISBN: 3-89722-296-5
|
|
MIBS and MILS Series
|
9. |
"Organometallics in Environment and Toxicology"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2010, 7, in press.
Royal Society of Chemistry, Cambridge, UK.
ISBN: 978-1-84755-177-1
ISSN: 1559-0836
|
8. |
"Metal-Carbon Bonds in Enzymes and Cofactors"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2009, 6, 510 pp.
Royal Society of Chemistry, Cambridge, UK.
ISBN: 978-1-84755-915-9
ISSN: 1559-0836
|
7. |
"Metallothioneins and Related Chelators"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2009, 5, 514 pp.
Royal Society of Chemistry, Cambridge, UK.
ISBN: 978-1-84755-899-2
ISSN: 1559-0836
|
6. |
"Biomineralization. From Nature to Application"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2008, 4, 671 pp.
John Wiley & Sons, Chichester, UK.
ISBN: 978-0-470-03525-2
ISSN: 1559-0836
|
5. |
"TheUbiquitous Roles of Cytochrome P450 Proteins"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2007, 3, 652 pp.
John Wiley & Sons, Chichester, UK.
ISBN: 978-0-470-01672-5
ISSN: 1559-0836
|
4. |
"Nickel and Its Surprising Impact in Nature"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2007, 2, 702 pp.
John Wiley & Sons, Chichester, UK.
ISBN: 978-0-470-01671-8
ISSN: 1559-0836
|
3. |
"Neurodegenerative Diseases and Metal Ions"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Life Sci., 2006, 1, 474 pp.
John Wiley & Sons, Chichester, UK.
ISBN: 978-0-470-01488-2
ISSN: 1559-0836
|
2. |
"Biogeochemistry, Availability, and Transport of Metals in the Environment"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Biol. Syst., 2005, 44, 498 pp.
Taylor & Francis Group, Boca Raton, FL, USA.
ISBN: 0-8493-3820-4
|
1. |
"Biogeochemical Cycles in Elements"
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Editors)
Met. Ions Biol. Syst., 2005, 43, 301 pp.
Taylor & Francis Group, Boca Raton, FL, USA.
ISBN: 0-8493-3807-7
|